Noto anche come
Chimotripsina
Nome ufficiale
Chimotripsina fecale
Ultima Revisione:
Ultima Modifica: 27.07.2020.
In Sintesi
Perché fare il test?

Per contribuire a rilevare e valutare l’insufficienza pancreatica.

Quando fare il test?

In presenza di sintomi quali diarrea persistente, produzione di feci maleodoranti, grasse e voluminose (steatorrea), malnutrizione, malassorbimento e carenza vitaminica; se si sospetta un’insufficienza pancreatica.

Che tipo di campione viene richiesto?

Un campione di feci non contaminato da urina.

 

Il test richiede una preparazione?

In soggetti che assumono enzimi pancreatici può essere consigliato di interrompere l'assunzione 5 giorni prima di sottoporsi al test.

L'Esame

La chimotripsina è un enzima responsabile della digestione delle proteine nell’intestino tenue. Questo esame rileva la concentrazione di chimotripsina presente nelle feci al fine di valutare la funzionalità pancreatica.

Il suo precursore inattivo, il chimotripsinogeno, è prodotto nel pancreas e trasportato nell’intestino tenue, dove viene attivato a chimotripsina. É uno degli enzimi responsabili della degradazione delle proteine assunte con la dieta a piccoli frammenti chiamati peptidi. La chimotripsina, se il pancreas funziona normalmente, è rilevabile nelle feci.

I soggetti affetti da disfunzioni pancreatiche possono presentare ostruzione dei dotti pancreatici o distruzione o danneggiamento delle cellule producenti chimoptripsinogeno. Questo tipo di lesioni può comportare l’insorgenza dell'insufficienza pancreatica con conseguente diminuzione della quantità di enzimi pancreatici trasportati nell’intestino tenue ed inadeguata digestione degli alimenti. Questa condizione può essere conseguenza di pancreatiti croniche o tumori pancreatici.

Gli intervalli di riferimento dipendono da molteplici fattori, quali l’età e il sesso del paziente, la popolazione di riferimento e il metodo utilizzato per l’esecuzione dell’esame. Il risultato numerico di un test può pertanto avere significati diversi in laboratori differenti.

Per queste ragioni, nel presente sito web non vengono riportati gli intervalli di riferimento. Per la valutazione dei risultati dei test, Lab Tests Online raccomanda di riferirsi ai valori di riferimento forniti dal laboratorio nel quale questi sono stati eseguiti. Gli intervalli di riferimento di ciascun test sono riportati sul referto di laboratorio, accanto al nome ed al risultato dello stesso. Per alcuni esempi clicca qui.

Per maggiori informazioni si rimanda agli articoli: Gli Intervalli di Riferimento ed il loro Significato e Comprendere il Referto di Laboratorio.

Se il sottoporsi alle analisi mediche provoca stati d'ansia o di disagio, si consiglia di leggere uno o più di questi articoli:

Come fare fronte alla paura, al disagio ed all'ansia da test, Suggerimenti sui test ematici, Suggerimenti per aiutare i bambini ad affrontare un test medico, Suggerimenti per aiutare l'anziano ad affrontare un test medico.

Un altro articolo, Il prelievo ematico: Breve viaggio nel laboratorio, chiarisce le modalità di prelievo del campione ematico.

Accordion Title
Come e Perché
Accordion Title
Domande Frequenti
Fonti

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2020 review performed by Uvaraj Uddayasankar, PhD, FCACB, Clinical Biochemist, LifeLabs ON.

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